Guillotina Boss Guide
How to prepare, survive the opener, and beat Guillotina safely in Mewgenics.
Best beaten by spacing, safe repositioning, and punishing after commitment.
How to prepare for Guillotina
Before the fightAppears during a later home-base defense sequence after the Boneyard progression line.
- •7 in-game days
- •4 retired cats
- •1 durable frontliner
- •1 ranged damage dealer
- •1 mobility / escape unit
- •1 healer or stabilizer
- •Slow units that cannot recover from pull or trample pressure
- •Cats that need tight formations to function
- •Underbuilt retired cats with weak survivability
Fast answer
Read this firstClaim open lanes early and do not start boxed near edges or objects. Use the first turns to deny easy approach paths instead of forcing damage.
- •Standing in her approach lane: she tramples to close, then uses melee-range CC and damage.
- •Getting pulled into melee range: once grouped, follow-up AOE and throws punish you hard.
- •Letting the 2x2 body pin you near edges or corners: you lose escape tiles and die to follow-up.
- •Deny clean trample lanes with spread positioning and side-steps.
- •Keep at least one escape tile behind each unit to survive pull or knockback pressure.
- •Punish after Guillotina commits to a lane or a major melee action, not before.
Answerbook (how to not die)
- •Standing in her approach lane: she tramples to close, then uses melee-range CC and damage.
- •Getting pulled into melee range: once grouped, follow-up AOE and throws punish you hard.
- •Letting the 2x2 body pin you near edges or corners: you lose escape tiles and die to follow-up.
- •Deny clean trample lanes with spread positioning and side-steps.
- •Keep at least one escape tile behind each unit to survive pull or knockback pressure.
- •Punish after Guillotina commits to a lane or a major melee action, not before.
- •Never stack in a straight line in front of her.
- •End turns with 1–2 open tiles behind your units whenever possible.
- •Fight in open space; avoid corners where a 2x2 body can trap your team.
- •Do not over-clump your backline behind a single frontline unit.
- •Claim open lanes early and do not start boxed near edges or objects.
- •Use the first turns to deny easy approach paths instead of forcing damage.
- •Bait a commit, then punish during her recovery positioning.
- •If a unit gets displaced, stabilize formation first before spending your best damage.
- •Close only when lanes are safe.
- •Do not all-in while your team is clustered near her body or trapped near the map edge.
Source: house-fights.csv + site editorial synthesis · Last tested: 2026-03-30 · Some move values are still being confirmed in live runs.
About Guillotina
Guillotina is a large 2x2 bruiser-style boss that becomes dangerous once she closes into melee. Most losses come from bad spacing, getting trapped near edges, or allowing her clean trample and pull lanes.
Why players lose this fight
Guillotina is a large 2x2 bruiser-style boss that becomes dangerous once she closes into melee. Most losses come from bad spacing, getting trapped near edges, or allowing her clean trample and pull lanes. The fight is mainly defined by bonus turns, trample, throw, aoe, zone pull. The most dangerous trigger identified so far is Actively seeks to walk over units to close distance..
Unverified phase notes
- •Some community notes mention a possible body/head split, but this is not stable enough to plan around yet.
- •Until fully verified, treat Guillotina primarily as a 2x2 trample bruiser with pull and melee follow-up.
- •Do not route your whole strategy around split-phase assumptions.
Quick facts
- Game
- Mewgenics
- Type
- Boss
- HP
- 400
- Movement
- 3
- Threat
- 2x2 Bruiser / Home Defense Pressure
- Risk
- High
- Last tested
- 2026-03-30
Related bosses
If you are struggling with Guillotina, these bosses share similar mechanics, pressure patterns, or positioning rules.